University of New Haven,
Department of Biology and Environmental Science
invites you to attend an informational lecture
on
Biofilms of Borrelia burgdorferi
and Clinical Application for Chronic
Borreliosis
Monday, July 7th, 2008
Lecture: 1:00 PM ~ 2:00 PM; Discussion:
2:00 PM ~ 3:00 PM
HOST: Eva Sapi Ph.D. Associate Professor
(UNH)
Admission is FREE and open to the
public
No registration required
Speaker: Dr. Alan MacDonald (St. Catherine
of Siena Medical Center, Smithtown, NY)
Dr. MacDonald has participated in
research activities related to tick borne
diseases since 1981, with pathologic studies
of Rocky Mountain Spotted Fever, Babesiosis,
Ehrlichiosis and
Borreliosis. In the 1989 he published
"Gestational Lyme Borreliosis, Implications
for the Fetus" which to this day is the
largest single collection of pathology cases
of human fetal autopsy material
demonstrating the transmission of
Borrelia burgdorferi from mother to
fetus in utero. In 1990, he published
"Clinical Implications of Delayed growth of
the Lyme disease spirochete, Borrelia
Burgdorferi", which demonstrated that some
strains of the spirochete divide very slowly
and require prolonged antibiotic therapy if
they are to be eradicated in the human host.
Recent work with Alzheimer's disease brain
tissues has been based on In situ DNA
hybridization techniques. Atypical forms of
Borrelia burgdorferi (ie forms which
are not regularly coiled corkscrew forms)
has been his career interest. MacDonald was
the first investigator to publish images of
Borrelia spirochetes without regular
corkscrew morphology. In his most recent
research, Dr. MacDonald studies the biofilm
formation of Borrelia burgdorferi and
its possible role in chronic Lyme disease.
LOCATION: University of New Haven,
Kaplan Hall Room#
107300 Boston Post Road, West Haven CT
06516 Direction at:
www.newhaven.edu website
For more information contact Dr. Eva Sapi at
(203) 479-4552 or email:
lyme2008@evasapi.net
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